RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy.

Zheng, Wenxin; Ranoa, Diana Rose E; Huang, Xiaona; Hou, Yuzhu; Yang, Kaiting; Poli, Elizabeth C; Beckett, Michael A; Fu, Yang-Xin; Weichselbaum, Ralph R

Zheng, Wenxin; Ranoa, Diana Rose E; Huang, Xiaona; Hou, Yuzhu; Yang, Kaiting; Poli, Elizabeth C; Beckett, Michael A; Fu, Yang-Xin; Weichselbaum, Ralph R.

Afiliação

Zheng W; Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois.
Ranoa DRE; Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois.
Huang X; Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois.
Hou Y; Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois.
Yang K; Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois.
Poli EC; Department of Surgery, University of Chicago, Chicago, Illinois.
Beckett MA; Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois.
Fu YX; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas. rrw@radonc.uchicago.edu yang-xin.fu@utsouthwestern.edu.
Weichselbaum RR; Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois. rrw@radonc.uchicago.edu yang-xin.fu@utsouthwestern.edu.

Cancer Res ; 80(24): 5633-5641, 2020 12 15.

Article em En | MEDLINE | ID: mdl-33087322

Assuntos

Células Dendríticas/patologia; RNA Helicases/genética; Neoplasias de Mama Triplo Negativas/radioterapia; Animais; Linfócitos T CD8-Positivos; Linhagem Celular Tumoral; Proteína DEAD-box 58/genética; Proteína DEAD-box 58/metabolismo; Células Dendríticas/efeitos da radiação; Feminino; Regulação Neoplásica da Expressão Gênica; Humanos; Helicase IFIH1 Induzida por Interferon/genética; Helicase IFIH1 Induzida por Interferon/metabolismo; Interferon gama/metabolismo; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Poli I-C/farmacologia; RNA Helicases/metabolismo; Radiação Ionizante; Receptores Imunológicos/genética; Receptores Imunológicos/metabolismo; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Neoplasias de Mama Triplo Negativas/genética; Neoplasias de Mama Triplo Negativas/mortalidade

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / RNA Helicases / Neoplasias de Mama Triplo Negativas Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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