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Complement activation and endothelial perturbation parallel COVID-19 severity and activity.
Cugno, Massimo; Meroni, Pier Luigi; Gualtierotti, Roberta; Griffini, Samantha; Grovetti, Elena; Torri, Adriana; Lonati, Paola; Grossi, Claudia; Borghi, Maria Orietta; Novembrino, Cristina; Boscolo, Massimo; Uceda Renteria, Sara Colonia; Valenti, Luca; Lamorte, Giuseppe; Manunta, Maria; Prati, Daniele; Pesenti, Antonio; Blasi, Francesco; Costantino, Giorgio; Gori, Andrea; Bandera, Alessandra; Tedesco, Francesco; Peyvandi, Flora.
Afiliação
  • Cugno M; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy. Electronic address: massimo.cugno@unimi.it.
  • Meroni PL; Immunorheumatology Research Laboratory; IRCCS Istituto Auxologico Italiano, Milan, Italy.
  • Gualtierotti R; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Griffini S; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Grovetti E; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Torri A; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Lonati P; Immunorheumatology Research Laboratory; IRCCS Istituto Auxologico Italiano, Milan, Italy.
  • Grossi C; Immunorheumatology Research Laboratory; IRCCS Istituto Auxologico Italiano, Milan, Italy.
  • Borghi MO; Immunorheumatology Research Laboratory; IRCCS Istituto Auxologico Italiano, Milan, Italy; Università degli Studi di Milano, Department of Clinical Sciences and Community Health, Milan, Italy.
  • Novembrino C; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Boscolo M; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
  • Uceda Renteria SC; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Virology Unit, Milan, Italy.
  • Valenti L; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Transfusion Medicine and Hematology, Milan, Italy.
  • Lamorte G; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Transfusion Medicine and Hematology, Milan, Italy.
  • Manunta M; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Transfusion Medicine and Hematology, Milan, Italy.
  • Prati D; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Transfusion Medicine and Hematology, Milan, Italy.
  • Pesenti A; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Anesthesia, Critical Care and Emergency, Milan, Italy.
  • Blasi F; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Respiratory Unit and Cystic Fibrosis Adult Center, Milan, Italy.
  • Costantino G; Università degli Studi di Milano, Department of Clinical Sciences and Community Health, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Emergency Department, Milan, Italy.
  • Gori A; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Infectious Disease Unit, Milan, Italy.
  • Bandera A; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Infectious Disease Unit, Milan, Italy.
  • Tedesco F; Immunorheumatology Research Laboratory; IRCCS Istituto Auxologico Italiano, Milan, Italy.
  • Peyvandi F; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Internal Medicine and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
J Autoimmun ; 116: 102560, 2021 01.
Article em En | MEDLINE | ID: mdl-33139116
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Biomarcadores / Ativação do Complemento / COVID-19 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endotélio Vascular / Biomarcadores / Ativação do Complemento / COVID-19 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article