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dUTPase inhibition confers susceptibility to a thymidylate synthase inhibitor in DNA-repair-defective human cancer cells.
Yokogawa, Tatsushi; Yano, Wakako; Tsukioka, Sayaka; Osada, Akiko; Wakasa, Takeshi; Ueno, Hiroyuki; Hoshino, Takuya; Yamamura, Keisuke; Fujioka, Akio; Fukuoka, Masayoshi; Ohkubo, Shuichi; Matsuo, Kenichi.
Afiliação
  • Yokogawa T; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Yano W; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Tsukioka S; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Osada A; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Wakasa T; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Ueno H; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Hoshino T; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Yamamura K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Fujioka A; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Fukuoka M; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Ohkubo S; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
  • Matsuo K; Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Japan.
Cancer Sci ; 112(1): 422-432, 2021 Jan.
Article em En | MEDLINE | ID: mdl-33140501
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Pirofosfatases / Sulfonamidas / Floxuridina / Reparo do DNA Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Pirofosfatases / Sulfonamidas / Floxuridina / Reparo do DNA Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article