Angiotensin II Type 2 Receptor Modulates Synovial Macrophage Polarization by Inhibiting GRK2 Membrane Translocation in a Rat Model of Collagen-Induced Arthritis.

Wang, Xinming; Tu, Jiajie; Jiang, Ji; Zhang, Qiaolin; Liu, Qi; Körner, Heinrich; Wu, Jingjing; Wu, Huaxun; Wei, Wei

Wang, Xinming; Tu, Jiajie; Jiang, Ji; Zhang, Qiaolin; Liu, Qi; Körner, Heinrich; Wu, Jingjing; Wu, Huaxun; Wei, Wei.

Afiliação

Wang X; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui 230032, China; and.
Tu J; Department of Pharmacy, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China.
Jiang J; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui 230032, China; and.
Zhang Q; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui 230032, China; and.
Liu Q; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui 230032, China; and.
Körner H; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui 230032, China; and.
Wu J; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui 230032, China; and.
Wu H; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui 230032, China; and.
Wei W; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, Anhui 230032, China; and wwei@ahmu.edu.cn wuhuaxun@ahmu.edu.cn.

J Immunol ; 205(11): 3141-3153, 2020 12 01.

Article em En | MEDLINE | ID: mdl-33148713

Assuntos

Artrite Experimental/induzido quimicamente; Artrite Experimental/metabolismo; Colágeno/farmacologia; Quinase 2 de Receptor Acoplado a Proteína G/metabolismo; Macrófagos/metabolismo; Receptor Tipo 2 de Angiotensina/metabolismo; Membrana Sinovial/metabolismo; Animais; Artrite Reumatoide/induzido quimicamente; Artrite Reumatoide/metabolismo; Modelos Animais de Doenças; Feminino; Humanos; Inflamação/induzido quimicamente; Inflamação/metabolismo; Macrófagos/efeitos dos fármacos; Camundongos; Transporte Proteico/fisiologia; Ratos; Ratos Sprague-Dawley; Transdução de Sinais/fisiologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Experimental / Membrana Sinovial / Colágeno / Receptor Tipo 2 de Angiotensina / Quinase 2 de Receptor Acoplado a Proteína G / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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