Mountain ginseng inhibits skeletal muscle atrophy by decreasing muscle RING ï¬nger protein-1 and atrogin1 through forkhead box O3 in L6 myotubes.

Seok, Young Mi; Yoo, Jae-Myung; Nam, Yoonju; Kim, Jungeun; Kim, Jin Soo; Son, Jun-Ho; Kim, Hyo Jung

Mountain ginseng inhibits skeletal muscle atrophy by decreasing muscle RING ï¬nger protein-1 and atrogin1 through forkhead box O3 in L6 myotubes.

Seok, Young Mi; Yoo, Jae-Myung; Nam, Yoonju; Kim, Jungeun; Kim, Jin Soo; Son, Jun-Ho; Kim, Hyo Jung.

Afiliação

Seok YM; Korean Medicine R&D Team 1, National Institute for Korean Medicine Development, Gyeongsan, 38540, Republic of Korea. Electronic address: abbamaria@hanmail.net.
Yoo JM; Korean Medicine R&D Team 1, National Institute for Korean Medicine Development, Gyeongsan, 38540, Republic of Korea. Electronic address: imyoo@nikom.or.kr.
Nam Y; Korean Medicine R&D Team 1, National Institute for Korean Medicine Development, Gyeongsan, 38540, Republic of Korea. Electronic address: juyoonnam@gmail.com.
Kim J; Korean Medicine R&D Team 1, National Institute for Korean Medicine Development, Gyeongsan, 38540, Republic of Korea. Electronic address: astely88@hanmail.net.
Kim JS; Korean Medicine R&D Team 1, National Institute for Korean Medicine Development, Gyeongsan, 38540, Republic of Korea. Electronic address: 1211pepero@nikom.or.kr.
Son JH; Korean Medicine R&D Team 1, National Institute for Korean Medicine Development, Gyeongsan, 38540, Republic of Korea. Electronic address: bio115@nikom.or.kr.
Kim HJ; Korean Medicine R&D Team 1, National Institute for Korean Medicine Development, Gyeongsan, 38540, Republic of Korea. Electronic address: indersee31@nikom.or.kr.

J Ethnopharmacol ; 270: 113557, 2021 Apr 24.

Article em En | MEDLINE | ID: mdl-33161026

Assuntos

Proteína Forkhead Box O3/metabolismo; Proteínas Musculares/metabolismo; Músculo Esquelético/efeitos dos fármacos; Atrofia Muscular/tratamento farmacológico; Panax/química; Extratos Vegetais/farmacologia; Complexo Repressor Polycomb 1/metabolismo; Proteínas Ligases SKP Culina F-Box/metabolismo; Ubiquitina-Proteína Ligases/metabolismo; Animais; Diferenciação Celular/efeitos dos fármacos; Linhagem Celular; Dexametasona/toxicidade; Proteína Forkhead Box O3/genética; Fibras Musculares Esqueléticas/efeitos dos fármacos; Proteínas Musculares/genética; Atrofia Muscular/induzido quimicamente; Atrofia Muscular/metabolismo; Atrofia Muscular/patologia; Mioblastos/efeitos dos fármacos; Mioblastos/metabolismo; Extratos Vegetais/uso terapêutico; RNA Polimerase II/metabolismo; Ratos Sprague-Dawley; Receptores de Glucocorticoides/metabolismo; Proteínas Ligases SKP Culina F-Box/genética; Proteínas com Motivo Tripartido/genética; Proteínas com Motivo Tripartido/metabolismo; Ubiquitina-Proteína Ligases/genética

Palavras-chave

Forkhead box O3; Glucocorticoid receptor; Mountain ginseng; MuRF1; Skeletal muscle atrophy; atrogin1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Atrofia Muscular / Músculo Esquelético / Ubiquitina-Proteína Ligases / Proteínas Ligases SKP Culina F-Box / Complexo Repressor Polycomb 1 / Proteína Forkhead Box O3 / Panax / Proteínas Musculares Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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