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Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes.
Marshall, A; Kasturiarachchi, J; Datta, P; Guo, Y; Deltcheva, E; James, C; Brown, J; May, G; Anandagoda, N; Jackson, I; Howard, J K; Ghazaly, E; Brooks, S; Khwaja, A; Araki, M; Araki, K; Linch, D; Lord, G M; Enver, T; Nimmo, R.
Afiliação
  • Marshall A; UCL Cancer Institute, University College London, London, UK.
  • Kasturiarachchi J; UCL Cancer Institute, University College London, London, UK.
  • Datta P; UCL Cancer Institute, University College London, London, UK.
  • Guo Y; UCL Cancer Institute, University College London, London, UK.
  • Deltcheva E; UCL Cancer Institute, University College London, London, UK.
  • James C; UCL Cancer Institute, University College London, London, UK.
  • Brown J; The Institute of Cancer Research, London, UK.
  • May G; UCL Cancer Institute, University College London, London, UK.
  • Anandagoda N; UCL Cancer Institute, University College London, London, UK.
  • Jackson I; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Howard JK; School of Immunology and Microbial Sciences, King's College London, London, UK.
  • Ghazaly E; School of Life Course Sciences, King's College London, London, UK.
  • Brooks S; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Khwaja A; Medicines and Healthcare Products Regulatory Agency (MHRA), London, UK.
  • Araki M; UCL Cancer Institute, University College London, London, UK.
  • Araki K; UCL Cancer Institute, University College London, London, UK.
  • Linch D; Institute of Resource Development and Analysis, Kumamoto University, Kumamoto, Japan.
  • Lord GM; Institute of Resource Development and Analysis, Kumamoto University, Kumamoto, Japan.
  • Enver T; UCL Cancer Institute, University College London, London, UK.
  • Nimmo R; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Sci Rep ; 10(1): 19390, 2020 11 10.
Article em En | MEDLINE | ID: mdl-33173219
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Regulação Leucêmica da Expressão Gênica / Proteínas de Homeodomínio / MicroRNAs / Isocitrato Desidrogenase Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Regulação Leucêmica da Expressão Gênica / Proteínas de Homeodomínio / MicroRNAs / Isocitrato Desidrogenase Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article