A unified linear mixed model for familial relatedness and population structure in genetic association studies.

DeVogel, Nicholas; Auer, Paul L; Manansala, Regina; Rau, Andrea; Wang, Tao

DeVogel, Nicholas; Auer, Paul L; Manansala, Regina; Rau, Andrea; Wang, Tao.

Afiliação

DeVogel N; Division of Biostatistics, Institute for Health and Equity, Milwaukee, Wisconsin, USA.
Auer PL; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Manansala R; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Rau A; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Wang T; INRAE, AgroParisTech, GABI, Université Paris-Saclay, Jouy-en-Josas, France.

Genet Epidemiol ; 45(3): 305-315, 2021 04.

Article em En | MEDLINE | ID: mdl-33175443

Assuntos

Genoma; Modelos Genéticos; Genes Dominantes; Estudos de Associação Genética; Genômica; Humanos

Palavras-chave

coancestry coefficient; familial relatedness; linear mixed model; population structure; random interactions; variance components

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genoma / Modelos Genéticos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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