Some Like It Sweet: Dendritic Cells Add Sugar to Their T(ea).

Kohlgruber, A C; Wang, C I; Elledge, S J

Kohlgruber, A C; Wang, C I; Elledge, S J.

Afiliação

Kohlgruber AC; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Genetics, Harvard University Medical School, Boston, MA 02115, USA.
Wang CI; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Genetics, Harvard University Medical School, Boston, MA 02115, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.
Elledge SJ; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address: selledge@genetics.med.harvard.edu.

Cell ; 183(4): 847-849, 2020 11 12.

Article em En | MEDLINE | ID: mdl-33186527

ABSTRACT

ABSTRACT

In this issue of Cell, Liu et al. present FucoID, a glycosyltransferase-mediated tagging platform, to biochemically label and capture antigen-specific T cells. With this technology, the authors isolate and characterize tumor-specific CD8+ and CD4+ T cells in murine tumor models. FucoID shows promise as a tool to enhance the understanding of anti-tumor immune responses.

Assuntos

Linfócitos T CD8-Positivos; Células Dendríticas; Animais; Antígenos de Neoplasias; Biotinilação; Linfócitos T CD4-Positivos; Camundongos; Açúcares

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Linfócitos T CD8-Positivos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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