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A novel carcinogenic PI3Kα mutation suggesting the role of helical domain in transmitting nSH2 regulatory signals to kinase domain.
Ghalamkari, Safoura; Alavi, Shahryar; Mianesaz, Hamidreza; Khosravian, Farinaz; Bahreini, Amir; Salehi, Mansoor.
Afiliação
  • Ghalamkari S; Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Alavi S; Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran.
  • Mianesaz H; Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Khosravian F; Cellular, Molecular and Genetics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Medical Genetics Research Center of Genome, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Bahreini A; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, PA, USA; KaryoGen, Isfahan, Iran. Electronic address: bahreini_amir@palinlab.com.
  • Salehi M; Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences, Isfahan, Iran; Cellular, Molecular and Genetics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Medical Genetics Research Center of Genome, Isfahan University of Medical Sciences, Isfahan, I
Life Sci ; 269: 118759, 2021 Mar 15.
Article em En | MEDLINE | ID: mdl-33189828
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Classe I de Fosfatidilinositol 3-Quinases / Carcinogênese / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Classe I de Fosfatidilinositol 3-Quinases / Carcinogênese / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article