Generation and Application of the Zebrafish <i>heg1</i> Mutant as a Cardiovascular Disease Model.

Lu, Shuxian; Hu, Mengyan; Wang, Zhihao; Liu, Hongkai; Kou, Yao; Lyu, Zhaojie; Tian, Jing

Generation and Application of the Zebrafish heg1 Mutant as a Cardiovascular Disease Model.

Lu, Shuxian; Hu, Mengyan; Wang, Zhihao; Liu, Hongkai; Kou, Yao; Lyu, Zhaojie; Tian, Jing.

Afiliação

Lu S; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710069, China.
Hu M; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710069, China.
Wang Z; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710069, China.
Liu H; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710069, China.
Kou Y; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710069, China.
Lyu Z; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710069, China.
Tian J; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Northwest University, Xi'an 710069, China.

Biomolecules ; 10(11)2020 11 12.

Article em En | MEDLINE | ID: mdl-33198188

Assuntos

Doenças Cardiovasculares/metabolismo; Modelos Animais de Doenças; Glicoproteínas de Membrana/metabolismo; Proteínas de Peixe-Zebra/metabolismo; Peixe-Zebra/genética; Animais; Circulação Sanguínea; Doenças Cardiovasculares/genética; Doenças Cardiovasculares/fisiopatologia; Feminino; Técnicas de Inativação de Genes; Frequência Cardíaca; Humanos; Masculino; Glicoproteínas de Membrana/genética; Mutação; Peixe-Zebra/metabolismo; Proteínas de Peixe-Zebra/genética

Palavras-chave

CRISPR/Cas9; Traditional Chinese Medicine (TCM); cardiovascular disease (CVD); dilated cardiomyopathy (DCM); drug screening; heg1; thrombosis; zebrafish model

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peixe-Zebra / Glicoproteínas de Membrana / Doenças Cardiovasculares / Proteínas de Peixe-Zebra / Modelos Animais de Doenças Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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