RNF213 gene mutation in circulating tumor DNA detected by targeted next-generation sequencing in the assisted discrimination of early-stage lung cancer from pulmonary nodules.

Jiang, Ning; Zhou, Jie; Zhang, Wenhao; Li, Peichao; Liu, Yu; Shi, Hubo; Zhang, Chengke; Wang, Yunshan; Zhou, Chengjun; Peng, Chuanliang; Zhang, Weiquan; Hao, Yingtao; Sun, Qifeng; Li, Yuliang; Zhao, Xiaogang

Jiang, Ning; Zhou, Jie; Zhang, Wenhao; Li, Peichao; Liu, Yu; Shi, Hubo; Zhang, Chengke; Wang, Yunshan; Zhou, Chengjun; Peng, Chuanliang; Zhang, Weiquan; Hao, Yingtao; Sun, Qifeng; Li, Yuliang; Zhao, Xiaogang.

Afiliação

Jiang N; Department of Thoracic Surgery, The Second Hospital of Shandong University, Jinan, China.
Zhou J; Key Laboratory of Chest Cancer, Shandong University, Jinan, China.
Zhang W; Cheeloo College of Medicine, Shandong University, Jinan, China.
Li P; Cheeloo College of Medicine, Shandong University, Jinan, China.
Liu Y; Cheeloo College of Medicine, Shandong University, Jinan, China.
Shi H; Department of Thoracic Surgery, The 960th Hospital of People's Liberation Army of China, Jinan, China.
Zhang C; Department of Thoracic Surgery, Shandong Provincial Chest Hospital, Jinan, China.
Wang Y; Department of Thoracic Surgery, The Second Hospital of Shandong University, Jinan, China.
Zhou C; Key Laboratory of Chest Cancer, Shandong University, Jinan, China.
Peng C; Department of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, China.
Zhang W; Pathology Department, The Second Hospital of Shandong University, Jinan, China.
Hao Y; Department of Thoracic Surgery, The Second Hospital of Shandong University, Jinan, China.
Sun Q; Key Laboratory of Chest Cancer, Shandong University, Jinan, China.
Li Y; Department of Thoracic Surgery, The Second Hospital of Shandong University, Jinan, China.
Zhao X; Key Laboratory of Chest Cancer, Shandong University, Jinan, China.

Thorac Cancer ; 12(2): 181-193, 2021 01.

Article em En | MEDLINE | ID: mdl-33200540

Assuntos

Adenosina Trifosfatases/genética; DNA Tumoral Circulante/genética; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Neoplasias Pulmonares/genética; Nódulos Pulmonares Múltiplos/genética; Mutação; Ubiquitina-Proteína Ligases/genética; Adenosina Trifosfatases/metabolismo; Adulto; Idoso; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Feminino; Humanos; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patologia; Masculino; Pessoa de Meia-Idade; Nódulos Pulmonares Múltiplos/metabolismo; Nódulos Pulmonares Múltiplos/patologia; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

Circulating tumor DNA (ctDNA); RNF213 gene; early diagnosis; lung cancer; targeted next generation sequencing (NGS)

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenosina Trifosfatases / Ubiquitina-Proteína Ligases / Nódulos Pulmonares Múltiplos / Sequenciamento de Nucleotídeos em Larga Escala / DNA Tumoral Circulante / Neoplasias Pulmonares / Mutação Tipo de estudo: Prognostic_studies / Screening_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google