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Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site.
Lee, Jaeyong; Worrall, Liam J; Vuckovic, Marija; Rosell, Federico I; Gentile, Francesco; Ton, Anh-Tien; Caveney, Nathanael A; Ban, Fuqiang; Cherkasov, Artem; Paetzel, Mark; Strynadka, Natalie C J.
Afiliação
  • Lee J; Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada.
  • Worrall LJ; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada.
  • Vuckovic M; Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada.
  • Rosell FI; Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada.
  • Gentile F; Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada.
  • Ton AT; Vancouver Prostate Centre, The University of British Columbia, Vancouver, BC, Canada.
  • Caveney NA; Vancouver Prostate Centre, The University of British Columbia, Vancouver, BC, Canada.
  • Ban F; Department of Biochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, BC, Canada.
  • Cherkasov A; Vancouver Prostate Centre, The University of British Columbia, Vancouver, BC, Canada.
  • Paetzel M; Vancouver Prostate Centre, The University of British Columbia, Vancouver, BC, Canada.
  • Strynadka NCJ; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada. mpaetzel@sfu.ca.
Nat Commun ; 11(1): 5877, 2020 11 18.
Article em En | MEDLINE | ID: mdl-33208735
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína Endopeptidases / Proteínas não Estruturais Virais / Betacoronavirus Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína Endopeptidases / Proteínas não Estruturais Virais / Betacoronavirus Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article