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Phenotypic Discovery of Neuroprotective Agents by Regulation of Tau Proteostasis via Stress-Responsive Activation of PERK Signaling.
Shin, Young-Hee; Cho, Hana; Choi, Bo Young; Kim, Jonghoon; Ha, Jaeyoung; Suh, Sang Won; Park, Seung Bum.
Afiliação
  • Shin YH; CRI Center for Chemical Proteomics, Department of Chemistry, Seoul National University, Seoul, 08826, Korea.
  • Cho H; Department of Biophysics and Chemical Biology, Seoul National University, Seoul, 08826, Korea.
  • Choi BY; Department of Physiology, College of Medicine, Hallym University, Chuncheon, 24252, Korea.
  • Kim J; CRI Center for Chemical Proteomics, Department of Chemistry, Seoul National University, Seoul, 08826, Korea.
  • Ha J; Present address: Department of Chemistry, Soongsil University, Seoul, 06978, Korea.
  • Suh SW; Department of Biophysics and Chemical Biology, Seoul National University, Seoul, 08826, Korea.
  • Park SB; Department of Physiology, College of Medicine, Hallym University, Chuncheon, 24252, Korea.
Angew Chem Int Ed Engl ; 60(4): 1831-1838, 2021 01 25.
Article em En | MEDLINE | ID: mdl-33210431

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas tau / Fármacos Neuroprotetores / EIF-2 Quinase / Descoberta de Drogas / Proteostase Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas tau / Fármacos Neuroprotetores / EIF-2 Quinase / Descoberta de Drogas / Proteostase Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article