Persistence of Maternal Anti-Rotavirus Immunoglobulin G in the Post-Rotavirus Vaccine Era.

Payne, Daniel C; McNeal, Monica; Staat, Mary Allen; Piasecki, Alexandra M; Cline, Allison; DeFranco, Emily; Goveia, Michelle G; Parashar, Umesh D; Burke, Rachel M; Morrow, Ardythe L

Payne, Daniel C; McNeal, Monica; Staat, Mary Allen; Piasecki, Alexandra M; Cline, Allison; DeFranco, Emily; Goveia, Michelle G; Parashar, Umesh D; Burke, Rachel M; Morrow, Ardythe L.

Afiliação

Payne DC; Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
McNeal M; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Staat MA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Piasecki AM; Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Cline A; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
DeFranco E; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Goveia MG; Merck & Co, Kenilworth, New Jersey, USA.
Parashar UD; Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Burke RM; Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Morrow AL; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

J Infect Dis ; 224(1): 133-136, 2021 07 02.

Article em En | MEDLINE | ID: mdl-33211872

ABSTRACT

ABSTRACT

To assess whether titers of anti-rotavirus immunoglobulin G persist during the post-rotavirus vaccine era, the Pediatric Respiratory and Enteric Virus Acquisition and Immunogenesis Longitudinal (PREVAIL) Cohort analyzed serum samples collected from Cincinnati-area mothers and young infants in 2017-2018. Rotavirus-specific antibodies continue to be transferred from US mothers to their offspring in the post-rotavirus vaccine era, despite dramatic decreases in childhood rotavirus gastroenteritis.

Assuntos

Anticorpos Antivirais/sangue; Imunoglobulina G/sangue; Vacinas contra Rotavirus/imunologia; Rotavirus/imunologia; Adolescente; Adulto; Feminino; Humanos; Lactente; Pessoa de Meia-Idade; Vacinação; Adulto Jovem

Palavras-chave

IgG; cohort; immunity; maternal antibodies; rotavirus; vaccine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Rotavirus / Vacinas contra Rotavirus / Anticorpos Antivirais Limite: Adolescent / Adult / Female / Humans / Infant / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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