Integrated molecular drivers coordinate biological and clinical states in melanoma.

Conway, Jake R; Dietlein, Felix; Taylor-Weiner, Amaro; AlDubayan, Saud; Vokes, Natalie; Keenan, Tanya; Reardon, Brendan; He, Meng Xiao; Margolis, Claire A; Weirather, Jason L; Haq, Rizwan; Schilling, Bastian; Stephen Hodi, F; Schadendorf, Dirk; Liu, David; Van Allen, Eliezer M

Conway, Jake R; Dietlein, Felix; Taylor-Weiner, Amaro; AlDubayan, Saud; Vokes, Natalie; Keenan, Tanya; Reardon, Brendan; He, Meng Xiao; Margolis, Claire A; Weirather, Jason L; Haq, Rizwan; Schilling, Bastian; Stephen Hodi, F; Schadendorf, Dirk; Liu, David; Van Allen, Eliezer M.

Afiliação

Conway JR; Division of Medical Sciences, Harvard University, Boston, MA, USA.
Dietlein F; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Taylor-Weiner A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
AlDubayan S; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Vokes N; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Keenan T; Division of Medical Sciences, Harvard University, Boston, MA, USA.
Reardon B; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
He MX; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Margolis CA; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Weirather JL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Haq R; Division of Genetics, Brigham and Women's Hospital, Boston, MA, USA.
Schilling B; Department of Medicine, King Saud bin Abdul-Aziz University for Health Sciences, Riyadh, Saudi Arabia.
Stephen Hodi F; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Schadendorf D; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Liu D; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Van Allen EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Nat Genet ; 52(12): 1373-1383, 2020 12.

Article em En | MEDLINE | ID: mdl-33230298

Assuntos

Distúrbios no Reparo do DNA/genética; GTP Fosfo-Hidrolases/genética; Melanoma/genética; Proteínas de Membrana/genética; Neurofibromina 1/genética; Proteínas Proto-Oncogênicas B-raf/genética; Neoplasias Cutâneas/genética; Reparo do DNA/genética; Predisposição Genética para Doença/genética; Humanos; Melanoma/patologia; Transdução de Sinais/genética; Neoplasias Cutâneas/patologia; Sequenciamento do Exoma

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Neurofibromina 1 / Proteínas Proto-Oncogênicas B-raf / Distúrbios no Reparo do DNA / GTP Fosfo-Hidrolases / Melanoma / Proteínas de Membrana Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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