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Ileal Transcriptomic Analysis in Paediatric Crohn's Disease Reveals IL17- and NOD-signalling Expression Signatures in Treatment-naïve Patients and Identifies Epithelial Cells Driving Differentially Expressed Genes.
Ashton, James J; Boukas, Konstantinos; Davies, James; Stafford, Imogen S; Vallejo, Andres F; Haggarty, Rachel; Coelho, Tracy A F; Batra, Akshay; Afzal, Nadeem A; Vadgama, Bhumita; Williams, Anthony P; Beattie, R Mark; Polak, Marta E; Ennis, Sarah.
Afiliação
  • Ashton JJ; Department of Human Genetics and Genomic Medicine, University of Southampton, Southampton, UK.
  • Boukas K; Department of Paediatric Gastroenterology, Southampton Children's Hospital, Southampton, UK.
  • Davies J; Wessex Investigational Sciences Hub, University of Southampton Faculty of Medicine, Southampton General Hospital, Southampton, UK.
  • Stafford IS; Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Vallejo AF; Department of Human Genetics and Genomic Medicine, University of Southampton, Southampton, UK.
  • Haggarty R; Institute for Life Sciences, University of Southampton, Southampton, UK.
  • Coelho TAF; Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Batra A; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, UK.
  • Afzal NA; Department of Paediatric Gastroenterology, Southampton Children's Hospital, Southampton, UK.
  • Vadgama B; Department of Paediatric Gastroenterology, Southampton Children's Hospital, Southampton, UK.
  • Williams AP; Department of Paediatric Gastroenterology, Southampton Children's Hospital, Southampton, UK.
  • Beattie RM; Department of Paediatric Histopathology, Southampton Children's Hospital, Southampton, UK.
  • Polak ME; Wessex Investigational Sciences Hub, University of Southampton Faculty of Medicine, Southampton General Hospital, Southampton, UK.
  • Ennis S; Institute for Life Sciences, University of Southampton, Southampton, UK.
J Crohns Colitis ; 15(5): 774-786, 2021 May 04.
Article em En | MEDLINE | ID: mdl-33232439
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Crohn / Interleucina-17 / Perfilação da Expressão Gênica / Células Epiteliais / Proteína Adaptadora de Sinalização NOD2 / Íleo Limite: Adolescent / Child / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Crohn / Interleucina-17 / Perfilação da Expressão Gênica / Células Epiteliais / Proteína Adaptadora de Sinalização NOD2 / Íleo Limite: Adolescent / Child / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article