Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia.

Creeden, Justin F; Alganem, Khaled; Imami, Ali S; Henkel, Nicholas D; Brunicardi, F Charles; Liu, Shi-He; Shukla, Rammohan; Tomar, Tushar; Naji, Faris; McCullumsmith, Robert E

Creeden, Justin F; Alganem, Khaled; Imami, Ali S; Henkel, Nicholas D; Brunicardi, F Charles; Liu, Shi-He; Shukla, Rammohan; Tomar, Tushar; Naji, Faris; McCullumsmith, Robert E.

Afiliação

Creeden JF; Department of Neurosciences, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
Alganem K; Department of Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
Imami AS; Department of Surgery, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 6038, USA.
Henkel ND; Department of Neurosciences, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
Brunicardi FC; Department of Neurosciences, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
Liu SH; Department of Neurosciences, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
Shukla R; Department of Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
Tomar T; Department of Surgery, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 6038, USA.
Naji F; Department of Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA.
McCullumsmith RE; Department of Surgery, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 6038, USA.

Int J Mol Sci ; 21(22)2020 Nov 21.

Article em En | MEDLINE | ID: mdl-33233470

Assuntos

Adenocarcinoma/genética; Tumor Desmoplásico de Pequenas Células Redondas/genética; Proteínas de Neoplasias/genética; Neoplasias Pancreáticas/genética; Adenocarcinoma/patologia; Tumor Desmoplásico de Pequenas Células Redondas/patologia; Receptor com Domínio Discoidina 1/genética; Progressão da Doença; Humanos; Neoplasias Pancreáticas/patologia; Proteínas Tirosina Quinases/genética; Proto-Oncogene Mas; Proteínas Proto-Oncogênicas c-hck/genética; Transdução de Sinais; Quinases da Família src/genética

Palavras-chave

SRC family kinases; desmoplasia; drug discovery; fibrosis; kinase therapy; pancreatic cancer; transcription factors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adenocarcinoma / Tumor Desmoplásico de Pequenas Células Redondas / Proteínas de Neoplasias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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