A 25-year retrospective study of Chlamydia psittaci in association with equine reproductive loss in Australia.
J Med Microbiol
; 70(2)2021 Feb.
Article
em En
| MEDLINE
| ID: mdl-33258756
ABSTRACT
Introduction. Chlamydia psittaci is primarily a pathogen of birds but can also cause disease in other species. Equine reproductive loss caused by C. psittaci has recently been identified in Australia where cases of human disease were also reported in individuals exposed to foetal membranes from an ill neonatal foal in New South Wales.Hypothesis/Gap Statement. The prevalence of C. psittaci in association with equine reproductive over time and in different regions of Australia is not known.Aim. This study was conducted to detect C. psittaci in equine abortion cases in Australia using archived samples spanning 25 years.Methodology. We tested for C. psittaci in 600 equine abortion cases reported in Australia between 1994 to 2019 using a Chlamydiaceae real-time quantitative PCR assay targeting the 16S rRNA gene followed by high-resolution melt curve analysis. Genotyping and phylogenetic analysis was performed on positive samples.Results. The overall prevalence of C. psittaci in material from equine abortion cases was 6.5â%. C. psittaci-positive cases were detected in most years that were represented in this study and occurred in Victoria (prevalence of 7.6â%), New South Wales (prevalence of 3.9â%) and South Australia (prevalence of 15.4â%). Genotyping and phylogenetic analysis showed that the C. psittaci detected in the equine abortion cases clustered with the parrot-associated 6BC clade (genotype A/ST24), indicating that infection of horses may be due to spillover from native Australian parrots.Conclusion. This work suggests that C. psittaci has been a signiï¬cant agent of equine abortion in Australia for several decades and underscores the importance of taking appropriate protective measures to avoid infection when handling equine aborted material.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psitacose
/
Doenças das Aves
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Chlamydophila psittaci
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Aborto Séptico
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Doenças dos Cavalos
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Animals
/
Pregnancy
País/Região como assunto:
Oceania
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article