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A Delphi panel on treatment of high disease activity relapsing remitting multiple sclerosis in the Netherlands.
Michels, Renée E; Peters, Michel L; Schiffers, Krijn Mh; Bouma, Paul A; Hengstman, Gerald Id; van Munster, Caspar Ep; Zeinstra, Esther; Voer, Gert De; Krol, Marieke.
Afiliação
  • Michels RE; Department of Real World & Analytics Solutions, IQVIA, Herikerbergweg 314, 1101 CT, Amsterdam, The Netherlands.
  • Peters ML; Department of Real World & Analytics Solutions, IQVIA, Herikerbergweg 314, 1101 CT, Amsterdam, The Netherlands.
  • Schiffers KM; Merck B.V., an affiliate of Merck KGaA, Darmstadt, Germany, Tupolevlaan 61, 1119 NW, Schiphol-Rijk, The Netherlands.
  • Bouma PA; Department of Neurology, Tergooi Ziekenhuis, van Riebeeckweg 212, 1213 XZ, Hilversum, The Netherlands.
  • Hengstman GI; Department of Neurology, Catharina Ziekenhuis, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands.
  • van Munster CE; Department of Neurology, Amphia Ziekenhuis, Molengracht 21, 4818 CK, Breda, The Netherlands.
  • Zeinstra E; Department of Neurology, Isala, Hoogeveenseweg 38, 7943 KA, Meppel, The Netherlands.
  • Voer G; Merck B.V., an affiliate of Merck KGaA, Darmstadt, Germany, Tupolevlaan 61, 1119 NW, Schiphol-Rijk, The Netherlands.
  • Krol M; Department of Real World & Analytics Solutions, IQVIA, Herikerbergweg 314, 1101 CT, Amsterdam, The Netherlands.
J Comp Eff Res ; 10(2): 93-100, 2021 02.
Article em En | MEDLINE | ID: mdl-33275036
ABSTRACT

Aim:

To gain insight into current treatment and barriers to optimal treatment for high disease activity relapsing remitting multiple sclerosis (MS) in the Netherlands. Materials &

methods:

A two-round Delphi panel using an online questionnaire was conducted. Seven MS neurologists from diverse locations in the Netherlands were invited to participate.

Result:

Out of the seven MS neurologists, five completed both questionnaire rounds.

Conclusion:

Effectiveness and side effects along with patient's lesion load were the most important factors for choosing a disease modifying therapy (DMTs). Respondents felt restricted to optimally treat their patients due to reimbursement restrictions for certain disease modifying therapies, although agreed that satisfactory treatment options are currently available. The answers show consensus between the participating MS neurologists with high certainty of answers.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Múltipla Recidivante-Remitente / Esclerose Múltipla Limite: Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Múltipla Recidivante-Remitente / Esclerose Múltipla Limite: Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article