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Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency.
Chu, Jen-Hwa; Zang, Wenlan; Vukmirovic, Milica; Yan, Xiting; Adams, Taylor; DeIuliis, Giuseppe; Hu, Buqu; Mihaljinec, Antun; Schupp, Jonas C; Becich, Michael J; Hochheiser, Harry; Gibson, Kevin F; Chen, Edward S; Morris, Alison; Leader, Joseph K; Wisniewski, Stephen R; Zhang, Yingze; Sciurba, Frank C; Collman, Ronald G; Sandhaus, Robert; Herzog, Erica L; Patterson, Karen C; Sauler, Maor; Strange, Charlie; Kaminski, Naftali.
Afiliação
  • Chu JH; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA jen-hwa.chu@yale.edu.
  • Zang W; Department of Biostatistics, Yale University School of Public Health, New Haven, Connecticut, USA.
  • Vukmirovic M; Department of Biostatistics, Yale University School of Public Health, New Haven, Connecticut, USA.
  • Yan X; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Adams T; Department of Medicine, Division of Respirology, McMaster University, Hamilton, Ontario, Canada.
  • DeIuliis G; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Hu B; Department of Biostatistics, Yale University School of Public Health, New Haven, Connecticut, USA.
  • Mihaljinec A; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Schupp JC; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Becich MJ; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Hochheiser H; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Gibson KF; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
  • Chen ES; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Morris A; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Leader JK; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Wisniewski SR; Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
  • Zhang Y; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Sciurba FC; Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Collman RG; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
  • Sandhaus R; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Herzog EL; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Patterson KC; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • Sauler M; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • Strange C; Department of Medicine, National Jewish Health, Denver, Colorado, USA.
  • Kaminski N; Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Thorax ; 76(2): 134-143, 2021 02.
Article em En | MEDLINE | ID: mdl-33303696

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de alfa 1-Antitripsina / Doença Pulmonar Obstrutiva Crônica / Redes Reguladoras de Genes Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de alfa 1-Antitripsina / Doença Pulmonar Obstrutiva Crônica / Redes Reguladoras de Genes Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article