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The vascular endothelial growth factor trap aflibercept induces vascular dysfunction and hypertension via attenuation of eNOS/NO signaling in mice.
Dong, Zhi-Chao; Wu, Ming-Ming; Zhang, Yun-Long; Wang, Qiu-Shi; Liang, Chen; Yan, Xiao; Zou, Lei-Xin; Chen, Chen; Han, Xiao; Zhang, Bo; Zhang, Zhi-Ren.
Afiliação
  • Dong ZC; Departments of Clinical Pharmacy and Cardiology, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, 150000, China.
  • Wu MM; Department of Cardiology, The First Affiliated Hospital, Dalian Medical University, Dalian, 116011, China.
  • Zhang YL; Departments of Clinical Pharmacy and Cardiology, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, 150000, China.
  • Wang QS; Department of Cardiology, The First Affiliated Hospital, Dalian Medical University, Dalian, 116011, China.
  • Liang C; Departments of Clinical Pharmacy and Cardiology, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, 150000, China.
  • Yan X; Departments of Clinical Pharmacy and Cardiology, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, 150000, China.
  • Zou LX; Department of Cardiology, The First Affiliated Hospital, Dalian Medical University, Dalian, 116011, China.
  • Chen C; Department of Cardiology, The First Affiliated Hospital, Dalian Medical University, Dalian, 116011, China.
  • Han X; Department of Cardiology, The First Affiliated Hospital, Dalian Medical University, Dalian, 116011, China.
  • Zhang B; Department of Cardiology, The First Affiliated Hospital, Dalian Medical University, Dalian, 116011, China.
  • Zhang ZR; Department of Cardiology, The First Affiliated Hospital, Dalian Medical University, Dalian, 116011, China. dalianzhangbo@yahoo.com.
Acta Pharmacol Sin ; 42(9): 1437-1448, 2021 Sep.
Article em En | MEDLINE | ID: mdl-33303990
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arginina / Doenças Vasculares / Proteínas Recombinantes de Fusão / Óxido Nítrico Sintase Tipo III / Hipertensão / Óxido Nítrico Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arginina / Doenças Vasculares / Proteínas Recombinantes de Fusão / Óxido Nítrico Sintase Tipo III / Hipertensão / Óxido Nítrico Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article