Conditional activation of an HIV-1 protease attenuated mutant by a leucine zipper dimerization motif.

Yu, Fu-Hsien; Huang, Kuo-Jung; Wang, Chin-Tien

Yu, Fu-Hsien; Huang, Kuo-Jung; Wang, Chin-Tien.

Afiliação

Yu FH; Department of Medical Research, National Yang-Ming University School of Medicine, Taiwan; Taipei Veterans General Hospital, Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taiwan.
Huang KJ; Department of Medical Research, National Yang-Ming University School of Medicine, Taiwan.
Wang CT; Department of Medical Research, National Yang-Ming University School of Medicine, Taiwan; Taipei Veterans General Hospital, Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taiwan. Electronic address: chintien@ym.edu.tw.

Virus Res ; 295: 198258, 2021 04 02.

Article em En | MEDLINE | ID: mdl-33316353

Assuntos

Protease de HIV; HIV-1; Zíper de Leucina; Dimerização; Protease de HIV/química; Protease de HIV/genética; HIV-1/fisiologia; Produtos do Gene gag do Vírus da Imunodeficiência Humana/genética; Produtos do Gene gag do Vírus da Imunodeficiência Humana/metabolismo

Palavras-chave

Gag cleavage; Gag-Pol; HIV-1; Leucine zipper; Protease activation; Virus maturation; p6pol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protease de HIV / Zíper de Leucina / HIV-1 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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