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Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML models with activating FLT3 mutations.
Miao, Hongzhi; Kim, EunGi; Chen, Dong; Purohit, Trupta; Kempinska, Katarzyna; Ropa, James; Klossowski, Szymon; Trotman, Winifred; Danet-Desnoyers, Gwenn; Cierpicki, Tomasz; Grembecka, Jolanta.
Afiliação
  • Miao H; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Kim E; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Chen D; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Purohit T; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Kempinska K; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Ropa J; Department of Microbiology and Immunology, School of Medicine, Indiana University, Indianapolis, IN; and.
  • Klossowski S; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Trotman W; Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Danet-Desnoyers G; Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Cierpicki T; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Grembecka J; Department of Pathology, University of Michigan, Ann Arbor, MI.
Blood ; 136(25): 2958-2963, 2020 12 17.
Article em En | MEDLINE | ID: mdl-33331926
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas / Tirosina Quinase 3 Semelhante a fms / Modelos Biológicos / Mutação Tipo de estudo: Clinical_trials Limite: Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Proto-Oncogênicas / Tirosina Quinase 3 Semelhante a fms / Modelos Biológicos / Mutação Tipo de estudo: Clinical_trials Limite: Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article