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Modulating target engagement of small molecules via drug delivery: approaches and applications in drug discovery and development.
Yang, Wenzhan; Bhattachar, Shobha N; Patel, Phenil J; Landis, Margaret; Patel, Dipal; Reid, Darren L; Duvnjak Romic, Marieta.
Afiliação
  • Yang W; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Boston, MA 02451, USA. Electronic address: wenzhan.yang@astrazeneca.com.
  • Bhattachar SN; Discovery Chemistry Research and Technologies, Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Patel PJ; Small Molecule Design and Development, Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Landis M; Molecular Pharmaceutics, Pharmaceutical Sciences, Pfizer Global Research and Development, Cambridge, MA 02139, USA.
  • Patel D; Department of Metabolism and Pharmacokinetics, Bristol-Myers Squibb, Inc., Princeton, NJ 08543, USA.
  • Reid DL; Pre-Pivotal Drug Product and Cellular Sciences, Drug Product Technologies, Amgen, Inc., Cambridge, MA 02142, USA.
  • Duvnjak Romic M; Technical Research & Development, Novartis Pharma AG, Basel 4002, Switzerland.
Drug Discov Today ; 26(3): 713-723, 2021 03.
Article em En | MEDLINE | ID: mdl-33333320

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Descoberta de Drogas / Desenvolvimento de Medicamentos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Descoberta de Drogas / Desenvolvimento de Medicamentos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article