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Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia.
Gimenez, Neus; Tripathi, Rupal; Giró, Ariadna; Rosich, Laia; López-Guerra, Mònica; López-Oreja, Irene; Playa-Albinyana, Heribert; Arenas, Fabian; Mas, José Manuel; Pérez-Galán, Patricia; Delgado, Julio; Campo, Elias; Farrés, Judith; Colomer, Dolors.
Afiliação
  • Gimenez N; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • Tripathi R; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.
  • Giró A; Anaxomics Biotech, Barcelona, Spain.
  • Rosich L; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • López-Guerra M; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • López-Oreja I; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.
  • Playa-Albinyana H; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • Arenas F; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.
  • Mas JM; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • Pérez-Galán P; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.
  • Delgado J; Hematopathology Unit, Department of Pathology, Hospital Clinic, IDIBAPS, Barcelona, Spain.
  • Campo E; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • Farrés J; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.
  • Colomer D; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Sci Rep ; 10(1): 22153, 2020 12 17.
Article em En | MEDLINE | ID: mdl-33335123
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Hidroximetilglutaril-CoA Redutases / Biologia de Sistemas / Avaliação Pré-Clínica de Medicamentos / Antineoplásicos Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Hidroximetilglutaril-CoA Redutases / Biologia de Sistemas / Avaliação Pré-Clínica de Medicamentos / Antineoplásicos Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article