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Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects.
Lee, Soyoung; Lee, Yujin; Kim, Andrew HyoungJin; Yoon, Sumin; Lee, Jieon; Ji, Sang Chun; Yoon, Seo Hyun; Lee, SeungHwan; Yu, Kyung-Sang; Jang, In-Jin; Cho, Joo-Youn.
Afiliação
  • Lee S; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address: sylee0829@snu.ac.kr.
  • Lee Y; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address: yoojinlee@snu.ac.kr.
  • Kim AH; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri, USA. Electronic address: andrewhkim87@gm
  • Yoon S; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address: smnyoon@snu.ac.kr.
  • Lee J; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address: jieon.lee27@gmail.com.
  • Ji SC; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address: scji@snu.ac.kr.
  • Yoon SH; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address: ena0512@snu.ac.kr.
  • Lee S; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address: leejh413@snu.ac.kr.
  • Yu KS; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: ksyu@snu.ac.kr.
  • Jang IJ; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea. Electronic address: ijjang@snu.ac.kr.
  • Cho JY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: joocho@snu.ac.kr.
Drug Metab Pharmacokinet ; 36: 100374, 2021 Feb.
Article em En | MEDLINE | ID: mdl-33348239
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Midazolam / Claritromicina / Citrus paradisi / Citocromo P-450 CYP3A / Mucosa Intestinal / Fígado Tipo de estudo: Clinical_trials Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Midazolam / Claritromicina / Citrus paradisi / Citocromo P-450 CYP3A / Mucosa Intestinal / Fígado Tipo de estudo: Clinical_trials Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article