HLA Class II Genotype Does Not Affect the Myelin Responsiveness of Multiple Sclerosis Patients.

Derdelinckx, Judith; Nkansah, Irene; Ooms, Naomi; Van Bruggen, Laura; Emonds, Marie-Paule; Daniëls, Liesbeth; Reynders, Tatjana; Willekens, Barbara; Cras, Patrick; Berneman, Zwi N; Cools, Nathalie

Derdelinckx, Judith; Nkansah, Irene; Ooms, Naomi; Van Bruggen, Laura; Emonds, Marie-Paule; Daniëls, Liesbeth; Reynders, Tatjana; Willekens, Barbara; Cras, Patrick; Berneman, Zwi N; Cools, Nathalie.

Afiliação

Derdelinckx J; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VaxInfectio), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Nkansah I; Division of Neurology, Antwerp University Hospital, 2650 Edegem, Belgium.
Ooms N; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VaxInfectio), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Van Bruggen L; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VaxInfectio), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Emonds MP; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VaxInfectio), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Daniëls L; Histocompatibility and Immunogenetics Laboratory, Red Cross-Flanders, 2650 Mechelen, Belgium.
Reynders T; Histocompatibility and Immunogenetics Laboratory, Red Cross-Flanders, 2650 Mechelen, Belgium.
Willekens B; Division of Neurology, Antwerp University Hospital, 2650 Edegem, Belgium.
Cras P; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VaxInfectio), Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Berneman ZN; Division of Neurology, Antwerp University Hospital, 2650 Edegem, Belgium.
Cools N; Division of Neurology, Antwerp University Hospital, 2650 Edegem, Belgium.

Cells ; 9(12)2020 12 17.

Article em En | MEDLINE | ID: mdl-33348629

Assuntos

Antígenos HLA/genética; Esclerose Múltipla Recidivante-Remitente/patologia; Proteína Básica da Mielina/metabolismo; Adulto; Idoso; Alelos; Estudos de Casos e Controles; Feminino; Genótipo; Cadeias alfa de HLA-DQ/genética; Cadeias beta de HLA-DQ/genética; Haplótipos; Humanos; Leucócitos Mononucleares/citologia; Leucócitos Mononucleares/efeitos dos fármacos; Leucócitos Mononucleares/metabolismo; Masculino; Pessoa de Meia-Idade; Esclerose Múltipla Recidivante-Remitente/genética; Proteína Básica da Mielina/química; Proteína Proteolipídica de Mielina/química; Proteína Proteolipídica de Mielina/metabolismo; Glicoproteína Mielina-Oligodendrócito/química; Glicoproteína Mielina-Oligodendrócito/metabolismo; Peptídeos/farmacologia; Adulto Jovem

Palavras-chave

HLA class II genotype; antigen-specific treatment; multiple sclerosis; myelin responsiveness

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Múltipla Recidivante-Remitente / Proteína Básica da Mielina / Antígenos HLA Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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