New phenolics from Uraria crinita (L.) DC.
Nat Prod Res
; 36(13): 3381-3388, 2022 Jul.
Article
em En
| MEDLINE
| ID: mdl-33350349
ABSTRACT
Reinvestigation of a methanol extract of Uraria crinita afforded a new 3- hydroxyisoflavanone, 3,5,7,2',4'-pentahydroxyisoflavanone (1), two new monoaryl glucosides, 3,4-dimethoxyphenyl 1-O-(6'-O-acetyl)-ß-D-glucopyranoside (2) and 3,4,5-trimethoxyphenyl 1-O-(6'-O-acetyl)-ß-D-glucopyranoside (3), in addition to three known compounds, 3'-O-methylorobol (4), robusflavone B (5), and apigenin (6). The structural elucidation of these compounds was achieved by analyses of their spectroscopic data (HR-ESI-MS, 1 D- and 2 D-NMR) and acidic hydrolysis. The U. crinita extracts and compounds 1-6 exhibited weak or no cytotoxic activity against KB, HepG2, Lu and MCF7 cell lines.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fabaceae
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article