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Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models.
Ku, Min-Wen; Bourgine, Maryline; Authié, Pierre; Lopez, Jodie; Nemirov, Kirill; Moncoq, Fanny; Noirat, Amandine; Vesin, Benjamin; Nevo, Fabien; Blanc, Catherine; Souque, Philippe; Tabbal, Houda; Simon, Emeline; Hardy, David; Le Dudal, Marine; Guinet, Françoise; Fiette, Laurence; Mouquet, Hugo; Anna, François; Martin, Annette; Escriou, Nicolas; Majlessi, Laleh; Charneau, Pierre.
Afiliação
  • Ku MW; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Bourgine M; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France; Molecular Virology and Vaccinology Unit, Virology Department, Institut Pasteur, Paris 75015, France.
  • Authié P; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Lopez J; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Nemirov K; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Moncoq F; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Noirat A; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Vesin B; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Nevo F; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Blanc C; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Souque P; Molecular Virology and Vaccinology Unit, Virology Department, Institut Pasteur, Paris 75015, France.
  • Tabbal H; Molecular Genetics of RNA Viruses Unit, Virology Department, Institut Pasteur, CNRS UMR3569, Université de Paris, Paris 75015, France.
  • Simon E; Molecular Genetics of RNA Viruses Unit, Virology Department, Institut Pasteur, CNRS UMR3569, Université de Paris, Paris 75015, France; Université de Paris, Paris 75006, France.
  • Hardy D; Experimental Neuropathology Unit, Global Health Department, Institut Pasteur, Paris 75015, France.
  • Le Dudal M; IMMR, 42 boulevard Jourdan, Paris 75014, France.
  • Guinet F; Lymphocytes and Immunity Unit, Immunology Department, Institut Pasteur, Paris 75015, France.
  • Fiette L; IMMR, 42 boulevard Jourdan, Paris 75014, France.
  • Mouquet H; Laboratory of Humoral Immunology, Immunology Department, Institut Pasteur, INSERM U1222, Paris, France.
  • Anna F; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France.
  • Martin A; Molecular Genetics of RNA Viruses Unit, Virology Department, Institut Pasteur, CNRS UMR3569, Université de Paris, Paris 75015, France.
  • Escriou N; Innovation Lab, Vaccines, Virology Department, Institut Pasteur, Paris 75015, France.
  • Majlessi L; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France. Electronic address: laleh.majlessi@pasteur.fr.
  • Charneau P; Institut Pasteur-TheraVectys Joint Lab, Virology Department, Institut Pasteur, Paris 75015, France; Molecular Virology and Vaccinology Unit, Virology Department, Institut Pasteur, Paris 75015, France. Electronic address: pierre.charneau@pasteur.fr.
Cell Host Microbe ; 29(2): 236-249.e6, 2021 02 10.
Article em En | MEDLINE | ID: mdl-33357418
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Administração Intranasal / Vacinas contra COVID-19 / SARS-CoV-2 / COVID-19 Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Administração Intranasal / Vacinas contra COVID-19 / SARS-CoV-2 / COVID-19 Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article