miR-30b-5p modulate renal epithelial-mesenchymal transition in diabetic nephropathy by directly targeting SNAI1.

Wang, Yanzhe; Liu, Yuyuan; Zhang, Ling; Bai, Linnan; Chen, Sijia; Wu, Hao; Sun, Linlin; Wang, Xiaoxia

Wang, Yanzhe; Liu, Yuyuan; Zhang, Ling; Bai, Linnan; Chen, Sijia; Wu, Hao; Sun, Linlin; Wang, Xiaoxia.

Afiliação

Wang Y; Department of Nephrology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu Y; Department of Nephrology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang L; Department of Nephrology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bai L; Department of Nephrology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen S; Department of Nephrology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wu H; Department of Nephrology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Sun L; Department of Nephrology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: llsunzj@sina.com.
Wang X; Department of Nephrology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: Omaha198501@163.com.

Biochem Biophys Res Commun ; 535: 12-18, 2021 01 08.

Article em En | MEDLINE | ID: mdl-33383483

Assuntos

Nefropatias Diabéticas/genética; Nefropatias Diabéticas/patologia; Transição Epitelial-Mesenquimal; Rim/metabolismo; MicroRNAs/genética; Fatores de Transcrição da Família Snail/genética; Animais; Caderinas/metabolismo; Linhagem Celular; Transição Epitelial-Mesenquimal/efeitos dos fármacos; Fibrose/genética; Fibrose/patologia; Glucose/farmacologia; Humanos; Hiperglicemia/genética; Hiperglicemia/patologia; Rim/patologia; Nefropatias/genética; Nefropatias/patologia; Masculino; Camundongos; Vimentina/metabolismo

Palavras-chave

Diabetic kidney disease (DN); Epithelial-to-mesenchymal transition (EMT); SNAI1; miR-30b-5p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Nefropatias Diabéticas / Transição Epitelial-Mesenquimal / Fatores de Transcrição da Família Snail / Rim Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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