Heteroclitic antibodies: differences in fine specificities between monoclonal antibodies directed against dinitrophenyl and trinitrophenyl haptens.
Int Arch Allergy Appl Immunol
; 85(2): 238-43, 1988.
Article
em En
| MEDLINE
| ID: mdl-3338862
ABSTRACT
The inhibition of binding of monoclonal antibodies by different haptens was studied using the 50% antibody binding assay. The binding of antidinitrophenyl and antitrinitrophenyl antibodies to dinitrophenylated or trinitrophenylated bovine serum albumin could be inhibited by monovalent dinitrophenyl or trinitrophenyl epsilon-aminocaproic acid. Some of the antibodies could be inhibited to a greater degree with the cross-reacting haptens than with the haptens homologous to the immunizing antigen, therefore these antibodies were heteroclitic.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trinitrobenzenos
/
Dinitrobenzenos
/
Haptenos
/
Anticorpos
/
Anticorpos Monoclonais
/
Nitrobenzenos
Limite:
Animals
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article