Benzo(a)pyrene-induced cytotoxicity, cell proliferation, DNA damage, and altered gene expression profiles in HT-29 human colon cancer cells.

Myers, Jeremy N; Harris, Kelly L; Rekhadevi, Perumalla V; Pratap, Siddharth; Ramesh, Aramandla

Myers, Jeremy N; Harris, Kelly L; Rekhadevi, Perumalla V; Pratap, Siddharth; Ramesh, Aramandla.

Afiliação

Myers JN; Department of Biochemistry, Cancer Biology, Neuroscience & Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd., Nashville, TN, 37208, USA.
Harris KL; Department of Biochemistry, Cancer Biology, Neuroscience & Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd., Nashville, TN, 37208, USA.
Rekhadevi PV; Department of Biotechnology, St. Francis College for Women, Hyderabad, Telangana, 500016, India.
Pratap S; School of Graduate Studies, Meharry Medical College, 1005 D.B. Todd Blvd., Nashville, TN, 37208, USA.
Ramesh A; Department of Biochemistry, Cancer Biology, Neuroscience & Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd., Nashville, TN, 37208, USA. aramesh@mmc.edu.

Cell Biol Toxicol ; 37(6): 891-913, 2021 12.

Article em En | MEDLINE | ID: mdl-33411230

Assuntos

Benzo(a)pireno; Neoplasias do Colo; Benzo(a)pireno/toxicidade; Proliferação de Células; Neoplasias do Colo/genética; Dano ao DNA; Humanos; Transcriptoma

Palavras-chave

BaP-DNA adducts; Benzo(a)pyrene; Biotransformation; Cell cycle; Cell proliferation; Colon cancer; HT-29 cells; Metabolites

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzo(a)pireno / Neoplasias do Colo Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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