Cardiometabolic traits mediating the effect of education on osteoarthritis risk: a Mendelian randomization study.

Gill, D; Karhunen, V; Malik, R; Dichgans, M; Sofat, N

Gill, D; Karhunen, V; Malik, R; Dichgans, M; Sofat, N.

Afiliação

Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; Institute for Infection and Immunity, St George's University of London, London, United Kingdom; St George's University Hospitals NHS Foundation Trust, London, United Kingdom. Elect
Karhunen V; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom. Electronic address: v.karhunen@imperial.ac.uk.
Malik R; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig-Maximilians-University (LMU), Munich, Germany. Electronic address: rainer.malik@med.uni-muenchen.de.
Dichgans M; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig-Maximilians-University (LMU), Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany. Electronic address: martin.dichgans@med.
Sofat N; Institute for Infection and Immunity, St George's University of London, London, United Kingdom; St George's University Hospitals NHS Foundation Trust, London, United Kingdom. Electronic address: nsofat@sgul.ac.uk.

Osteoarthritis Cartilage ; 29(3): 365-371, 2021 03.

Article em En | MEDLINE | ID: mdl-33422704

Assuntos

Pressão Sanguínea/genética; Fatores de Risco Cardiometabólico; LDL-Colesterol/genética; Escolaridade; Obesidade/epidemiologia; Osteoartrite/epidemiologia; Fumar/epidemiologia; Idoso; Índice de Massa Corporal; Feminino; Estudo de Associação Genômica Ampla; Humanos; Masculino; Análise de Mediação; Análise da Randomização Mendeliana; Pessoa de Meia-Idade; Obesidade/genética; Razão de Chances; Osteoartrite/genética; Fumar/genética

Palavras-chave

Cardiometabolic; Education; Mendelian randomization; Osteoarthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Pressão Sanguínea / Fumar / Escolaridade / Fatores de Risco Cardiometabólico / LDL-Colesterol / Obesidade Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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