Inorganic polyphosphate in platelet rich plasma accelerates re-epithelialization <i>in vitro</i> and <i>in vivo</i>.

Carney, Bonnie C; Simbulan-Rosenthal, Cynthia M; Gaur, Anirudh; Browne, Benjamin J; Moghe, Manish; Crooke, Elliott; Moffatt, Lauren T; Shupp, Jeffrey W; Rosenthal, Dean S

Inorganic polyphosphate in platelet rich plasma accelerates re-epithelialization in vitro and in vivo.

Carney, Bonnie C; Simbulan-Rosenthal, Cynthia M; Gaur, Anirudh; Browne, Benjamin J; Moghe, Manish; Crooke, Elliott; Moffatt, Lauren T; Shupp, Jeffrey W; Rosenthal, Dean S.

Afiliação

Carney BC; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Simbulan-Rosenthal CM; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, USA.
Gaur A; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Browne BJ; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Moghe M; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, USA.
Crooke E; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Moffatt LT; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Shupp JW; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Rosenthal DS; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, USA.

Regen Ther ; 15: 138-148, 2020 Dec.

Article em En | MEDLINE | ID: mdl-33426212

Palavras-chave

Inorganic polyphosphate; Keratinocytes; PPX1 exopolyphosphatase; Wound healing; endopolyphosphatase, PPN; epidermal growth factor, EGF; exopolyphosphatase, PPX; human foreskin fibroblasts, HFF; mammalian target of rapamycin, mTOR; platelet-derived growth factor, PDGF; platelet-poor plasma, PPP; platelet-rich plasma, PRP; polyP kinase, PPK; polyphosphates, polyP; reactive oxygen species, ROS; total body surface area, TBSA; transforming growth factor beta, TGFß; vacuolar transporter chaperone 4, VTC4

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article