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Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial.
Fisher, Michael J; Shih, Chie-Schin; Rhodes, Steven D; Armstrong, Amy E; Wolters, Pamela L; Dombi, Eva; Zhang, Chi; Angus, Steven P; Johnson, Gary L; Packer, Roger J; Allen, Jeffrey C; Ullrich, Nicole J; Goldman, Stewart; Gutmann, David H; Plotkin, Scott R; Rosser, Tena; Robertson, Kent A; Widemann, Brigitte C; Smith, Abbi E; Bessler, Waylan K; He, Yongzheng; Park, Su-Jung; Mund, Julie A; Jiang, Li; Bijangi-Vishehsaraei, Khadijeh; Robinson, Coretta Thomas; Cutter, Gary R; Korf, Bruce R; Blakeley, Jaishri O; Clapp, D Wade.
Afiliação
  • Fisher MJ; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Shih CS; Division of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.
  • Rhodes SD; Merck & Co., Inc., Kenilworth, NJ, USA.
  • Armstrong AE; Division of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.
  • Wolters PL; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Dombi E; Division of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.
  • Zhang C; Division of Pediatric Hematology/Oncology, Washington University School of Medicine, St. Louis, MO, USA.
  • Angus SP; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Johnson GL; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Packer RJ; Department of Medical and Molecular Genomics, Indiana University, Indianapolis, IN, USA.
  • Allen JC; Division of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.
  • Ullrich NJ; Department of Pharmacology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
  • Goldman S; Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Gutmann DH; Department of Pharmacology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
  • Plotkin SR; Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, Washington, DC, USA.
  • Rosser T; Department of Pediatrics, New York University School of Medicine, New York, NY, USA.
  • Robertson KA; Department of Neurology, Dana Farber/Boston Children's Hospital, Boston, MA, USA.
  • Widemann BC; Division of Hematology/Oncology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
  • Smith AE; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
  • Bessler WK; Department of Neurology and Neuro-Oncology, Massachusetts General Hospital, Boston, MA, USA.
  • He Y; Division of Neurology, Children's Hospital of Los Angeles, Los Angeles, CA, USA.
  • Park SJ; Division of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.
  • Mund JA; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Jiang L; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Bijangi-Vishehsaraei K; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Robinson CT; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Cutter GR; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Korf BR; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Blakeley JO; Division of Hematology/Oncology, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.
  • Clapp DW; Department of Biostatistics, University of Alabama Birmingham, Birmingham, AL, USA.
Nat Med ; 27(1): 165-173, 2021 01.
Article em En | MEDLINE | ID: mdl-33442015
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Neurofibromatose 1 / Neurofibroma Plexiforme / Anilidas Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Neurofibromatose 1 / Neurofibroma Plexiforme / Anilidas Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article