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Exosome Surface Display of IL12 Results in Tumor-Retained Pharmacology with Superior Potency and Limited Systemic Exposure Compared with Recombinant IL12.
Lewis, Nuruddeen D; Sia, Chang Ling; Kirwin, Katherine; Haupt, Sonya; Mahimkar, Gauri; Zi, Tong; Xu, Ke; Dooley, Kevin; Jang, Su Chul; Choi, Bryan; Boutin, Adam; Grube, Andrew; McCoy, Christine; Sanchez-Salazar, Jorge; Doherty, Michael; Gaidukov, Leonid; Estes, Scott; Economides, Kyriakos D; Williams, Douglas E; Sathyanarayanan, Sriram.
Afiliação
  • Lewis ND; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Sia CL; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Kirwin K; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Haupt S; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Mahimkar G; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Zi T; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Xu K; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Dooley K; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Jang SC; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Choi B; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Boutin A; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Grube A; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • McCoy C; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Sanchez-Salazar J; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Doherty M; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Gaidukov L; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Estes S; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Economides KD; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Williams DE; Codiak BioSciences Inc., Cambridge, Massachusetts.
  • Sathyanarayanan S; Codiak BioSciences Inc., Cambridge, Massachusetts. sriram.sathy@codiakbio.com.
Mol Cancer Ther ; 20(3): 523-534, 2021 03.
Article em En | MEDLINE | ID: mdl-33443094
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-12 / Exossomos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-12 / Exossomos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article