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Adaptive resistance to PI3Kα-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells.
Wang, Yu-Xiang; Zhang, Xu; Ma, Qing-Yang; Hu, Lan-Dian; Zhang, Xi; Wang, Yi; Xu, Lan; Yang, Chun-Hao; Tan, Cun; Kong, Xiang-Yin; Ding, Jian; Meng, Ling-Hua.
Afiliação
  • Wang YX; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China.
  • Zhang X; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China.
  • Ma QY; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, 100049, China.
  • Hu LD; Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, China.
  • Zhang X; Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, China.
  • Wang Y; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China.
  • Xu L; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China.
  • Yang CH; Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China.
  • Tan C; Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 200120, China.
  • Kong XY; Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 200120, China.
  • Ding J; Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai, 200031, China.
  • Meng LH; University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, 100049, China. jding@simm.ac.cn.
Cell Death Dis ; 12(1): 85, 2021 01 14.
Article em En | MEDLINE | ID: mdl-33446653
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Piperazinas / Pirróis / Morfolinas / Genômica / Inibidores de Proteínas Quinases / Sequenciamento de Nucleotídeos em Larga Escala / Carcinoma de Células Escamosas do Esôfago Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Piperazinas / Pirróis / Morfolinas / Genômica / Inibidores de Proteínas Quinases / Sequenciamento de Nucleotídeos em Larga Escala / Carcinoma de Células Escamosas do Esôfago Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article