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Large-scale association analyses identify host factors influencing human gut microbiome composition.
Kurilshikov, Alexander; Medina-Gomez, Carolina; Bacigalupe, Rodrigo; Radjabzadeh, Djawad; Wang, Jun; Demirkan, Ayse; Le Roy, Caroline I; Raygoza Garay, Juan Antonio; Finnicum, Casey T; Liu, Xingrong; Zhernakova, Daria V; Bonder, Marc Jan; Hansen, Tue H; Frost, Fabian; Rühlemann, Malte C; Turpin, Williams; Moon, Jee-Young; Kim, Han-Na; Lüll, Kreete; Barkan, Elad; Shah, Shiraz A; Fornage, Myriam; Szopinska-Tokov, Joanna; Wallen, Zachary D; Borisevich, Dmitrii; Agreus, Lars; Andreasson, Anna; Bang, Corinna; Bedrani, Larbi; Bell, Jordana T; Bisgaard, Hans; Boehnke, Michael; Boomsma, Dorret I; Burk, Robert D; Claringbould, Annique; Croitoru, Kenneth; Davies, Gareth E; van Duijn, Cornelia M; Duijts, Liesbeth; Falony, Gwen; Fu, Jingyuan; van der Graaf, Adriaan; Hansen, Torben; Homuth, Georg; Hughes, David A; Ijzerman, Richard G; Jackson, Matthew A; Jaddoe, Vincent W V; Joossens, Marie; Jørgensen, Torben.
Afiliação
  • Kurilshikov A; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. alexa.kur@gmail.com.
  • Medina-Gomez C; Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Bacigalupe R; The Generation R Study, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Radjabzadeh D; Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
  • Wang J; Center for Microbiology, VIB, Leuven, Belgium.
  • Demirkan A; Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Le Roy CI; Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
  • Raygoza Garay JA; Center for Microbiology, VIB, Leuven, Belgium.
  • Finnicum CT; Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Liu X; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Zhernakova DV; Section of Statistical Multi-Omics, Department of Clinical & Experimental Medicine, School of Biosciences & Medicine, University of Surrey, Guildford, UK.
  • Bonder MJ; Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.
  • Hansen TH; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Frost F; Division of Gastroenterology, Mount Sinai Hospital, Toronto, Ontario, Canada.
  • Rühlemann MC; Avera Institute of Human Genetics, Avera McKennan Hospital & University Health Center, Sioux Falls, SD, USA.
  • Turpin W; Center for Molecular Medicine and Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
  • Moon JY; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Kim HN; Laboratory of Genomic Diversity, Center for Computer Technologies, ITMO University, St. Petersburg, Russia.
  • Lüll K; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Barkan E; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Shah SA; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.
  • Fornage M; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Szopinska-Tokov J; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Wallen ZD; Division of Gastroenterology, Mount Sinai Hospital, Toronto, Ontario, Canada.
  • Borisevich D; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Agreus L; Medical Research Institute, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
  • Andreasson A; Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.
  • Bang C; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
  • Bedrani L; Department of Computer Science and Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Bell JT; COPSAC, Copenhagen University Hospital, Copenhagen, Denmark.
  • Bisgaard H; Institute of Molecular Medicine McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Boehnke M; Human Genetics Center School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Boomsma DI; Department of Psychiatry, Radboudumc, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, the Netherlands.
  • Burk RD; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Claringbould A; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Croitoru K; Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
  • Davies GE; Stress Research Institute, Stockholm University, Stockholm, Sweden.
  • van Duijn CM; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Duijts L; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Falony G; Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.
  • Fu J; COPSAC, Copenhagen University Hospital, Copenhagen, Denmark.
  • van der Graaf A; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Hansen T; Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
  • Homuth G; Department of Pediatrics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Hughes DA; Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Ijzerman RG; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Jackson MA; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Jaddoe VWV; Division of Gastroenterology, Mount Sinai Hospital, Toronto, Ontario, Canada.
  • Joossens M; Avera Institute of Human Genetics, Avera McKennan Hospital & University Health Center, Sioux Falls, SD, USA.
  • Jørgensen T; Biological Psychology, Vrije Universiteit, Amsterdam, the Netherlands.
Nat Genet ; 53(2): 156-165, 2021 02.
Article em En | MEDLINE | ID: mdl-33462485
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / Locos de Características Quantitativas / Microbioma Gastrointestinal Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / Locos de Características Quantitativas / Microbioma Gastrointestinal Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article