Elucidation of the Controlled-Release Behavior of Metoprolol Succinate from Directly Compressed Xanthan Gum/Chitosan Polymers: Computational and Experimental Studies.

Dadou, Suha M; El-Barghouthi, Musa I; Antonijevic, Milan D; Chowdhry, Babur Z; Badwan, Adnan A

Dadou, Suha M; El-Barghouthi, Musa I; Antonijevic, Milan D; Chowdhry, Babur Z; Badwan, Adnan A.

Afiliação

Dadou SM; Department of Pharmaceutical, Chemical & Environmental Science, Faculty of Engineering & Science, University of Greenwich, Medway Campus, Chatham Maritime, Kent ME4 4TB, United Kingdom.
El-Barghouthi MI; Department of Chemistry, The Hashemite University, P.O. Box 150459, Zarqa 13115, Jordan.
Antonijevic MD; Department of Chemistry, Isra University, Amman 11622, Jordan.
Chowdhry BZ; Department of Pharmaceutical, Chemical & Environmental Science, Faculty of Engineering & Science, University of Greenwich, Medway Campus, Chatham Maritime, Kent ME4 4TB, United Kingdom.
Badwan AA; Department of Pharmaceutical, Chemical & Environmental Science, Faculty of Engineering & Science, University of Greenwich, Medway Campus, Chatham Maritime, Kent ME4 4TB, United Kingdom.

ACS Biomater Sci Eng ; 6(1): 21-37, 2020 01 13.

Article em En | MEDLINE | ID: mdl-33463201

Assuntos

Quitosana; Metoprolol; Química Farmacêutica; Preparações de Ação Retardada; Polímeros; Polissacarídeos Bacterianos

Palavras-chave

Raman mapping; controlled-release polymeric matrixes; low molecular weight chitosan; metoprolol succinate; molecular dynamics simulations; pharmaceutical formulation; response surface method; tablet swelling; xanthan gum

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quitosana / Metoprolol Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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