A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette-Guèrin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-&#945;.

Tajiri, Kazuko; Imanaka-Yoshida, Kyoko; Tsujimura, Yusuke; Matsuo, Kazuhiro; Hiroe, Michiaki; Aonuma, Kazutaka; Ieda, Masaki; Yasutomi, Yasuhiro

A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette-Guèrin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-α.

Tajiri, Kazuko; Imanaka-Yoshida, Kyoko; Tsujimura, Yusuke; Matsuo, Kazuhiro; Hiroe, Michiaki; Aonuma, Kazutaka; Ieda, Masaki; Yasutomi, Yasuhiro.

Afiliação

Tajiri K; Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Tsukuba 305-0843, Japan.
Imanaka-Yoshida K; Department of Cardiology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.
Tsujimura Y; Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Matsuo K; Mie University Matrix Biology Research Center, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Hiroe M; Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Tsukuba 305-0843, Japan.
Aonuma K; Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama 189-0002, Japan.
Ieda M; Department of Research and Development, Japan BCG Laboratory, Kiyose 204-0022, Japan.
Yasutomi Y; Department of Cardiology, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.

Int J Mol Sci ; 22(2)2021 Jan 14.

Article em En | MEDLINE | ID: mdl-33466825

Assuntos

Vacina BCG/imunologia; Modelos Animais de Doenças; Epitopos de Linfócito T/imunologia; Miocardite/imunologia; Miosinas Ventriculares/imunologia; Animais; Vacina BCG/genética; Cardiomiopatia Dilatada/imunologia; Cardiomiopatia Dilatada/patologia; Cardiomiopatia Dilatada/fisiopatologia; Doença Crônica; Citocinas/imunologia; Citocinas/metabolismo; Ecocardiografia; Epitopos de Linfócito T/genética; Humanos; Interleucina-17/imunologia; Interleucina-17/metabolismo; Ativação Linfocitária; Masculino; Camundongos Endogâmicos BALB C; Miocardite/patologia; Miocardite/fisiopatologia; Proteínas Recombinantes/imunologia; Células Th1/imunologia; Células Th1/metabolismo; Células Th17/imunologia; Células Th17/metabolismo; Miosinas Ventriculares/genética

Palavras-chave

BCG; autoimmune myocarditis; autoimmunity; inflammatory dilated cardiomyopathy; myocarditis; recombinant BCG

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacina BCG / Epitopos de Linfócito T / Miosinas Ventriculares / Modelos Animais de Doenças / Miocardite Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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