Epidemiology of cytomegalovirus Infection among mothers and infants in Colombia.
J Med Virol
; 93(11): 6393-6397, 2021 11.
Article
em En
| MEDLINE
| ID: mdl-33475162
ABSTRACT
We assessed maternal and infant cytomegalovirus (CMV) infection in Colombia. Maternal serum was tested for CMV immunoglobulin G antibodies at a median of 10 (interquartile range 8-12) weeks gestation (n = 1501). CMV DNA polymerase chain reaction was performed on infant urine to diagnose congenital (≤21 days of life) and postnatal (>21 days) infection. Maternal CMV seroprevalence was 98.1% (95% confidence interval [CI] 97.5%-98.8%). Congenital CMV prevalence was 8.4 (95% CI 3.9%-18.3%; 6/711) per 1000 live births. Among 472 infants without confirmed congenital CMV infection subsequently tested at age 6 months, 258 (54.7%, 95% CI 50.2%-59.1%) had postnatal infection.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
/
Infecções por Citomegalovirus
/
Citomegalovirus
/
Anticorpos Antivirais
Tipo de estudo:
Clinical_trials
/
Risk_factors_studies
/
Screening_studies
Limite:
Adult
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Pregnancy
País/Região como assunto:
America do sul
/
Colombia
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article