To Degrade a MicroRNA, Destroy Its Argonaute Protein.
Mol Cell
; 81(2): 223-225, 2021 01 21.
Article
em En
| MEDLINE
| ID: mdl-33482091
ABSTRACT
Han et al. (2020) and Shi et al. (2020) report that the E3 ubiquitin ligase ZSWIM8 senses when an RNA and an Argonaute protein-bound microRNA are extensively base paired and directs Argonaute destruction by the proteasome. The result is degradation of the microRNA.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ubiquitina
/
MicroRNAs
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article