Niche-dependent inhibition of neural stem cell proliferation and oligodendrogenesis is mediated by the presence of myelin basic protein.

Lakshman, Nishanth; Bourget, Clara; Siu, Ricky; Bamm, Vladimir V; Xu, Wenjun; Harauz, George; Morshead, Cindi M

Lakshman, Nishanth; Bourget, Clara; Siu, Ricky; Bamm, Vladimir V; Xu, Wenjun; Harauz, George; Morshead, Cindi M.

Afiliação

Lakshman N; Department of Surgery, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Bourget C; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.
Siu R; Department of Surgery, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Bamm VV; Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.
Xu W; Department of Surgery, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Harauz G; Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Morshead CM; Department of Surgery, Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.

Stem Cells ; 39(6): 776-786, 2021 06.

Article em En | MEDLINE | ID: mdl-33529418

Assuntos

Diferenciação Celular/fisiologia; Proteína Básica da Mielina/metabolismo; Células-Tronco Neurais/metabolismo; Oligodendroglia/citologia; Animais; Proliferação de Células/efeitos dos fármacos; Meios de Cultivo Condicionados/farmacologia; Bainha de Mielina/metabolismo; Medula Espinal/metabolismo

Palavras-chave

forebrain; myelin basic protein; neural stem cells; niche; oligodendrocytes; spinal cord

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Oligodendroglia / Proteína Básica da Mielina / Células-Tronco Neurais Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google