Preclinical Evaluation of B7-H3-specific Chimeric Antigen Receptor T Cells for the Treatment of Acute Myeloid Leukemia.

Lichtman, Eben I; Du, Hongwei; Shou, Peishun; Song, Feifei; Suzuki, Kyogo; Ahn, Sarah; Li, Guangming; Ferrone, Soldano; Su, Lishan; Savoldo, Barbara; Dotti, Gianpietro

Lichtman, Eben I; Du, Hongwei; Shou, Peishun; Song, Feifei; Suzuki, Kyogo; Ahn, Sarah; Li, Guangming; Ferrone, Soldano; Su, Lishan; Savoldo, Barbara; Dotti, Gianpietro.

Afiliação

Lichtman EI; Division of Hematology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina. eben_lichtman@med.unc.edu.
Du H; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Shou P; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Song F; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina.
Suzuki K; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Ahn S; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina.
Li G; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Ferrone S; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina.
Su L; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Savoldo B; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina.
Dotti G; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.

Clin Cancer Res ; 27(11): 3141-3153, 2021 06 01.

Article em En | MEDLINE | ID: mdl-33531429

Assuntos

Antígenos B7/metabolismo; Imunoterapia Adotiva/métodos; Leucemia Mieloide Aguda/terapia; Terapia de Alvo Molecular/métodos; Receptores de Antígenos Quiméricos; Animais; Antígenos B7/genética; Linhagem Celular Tumoral; Citotoxicidade Imunológica; Modelos Animais de Doenças; Expressão Gênica; Leucemia Mieloide Aguda/genética; Leucemia Mieloide Aguda/metabolismo; Camundongos; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Imunoterapia Adotiva / Terapia de Alvo Molecular / Antígenos B7 / Receptores de Antígenos Quiméricos Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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