Interleukin-1ß, Oxidative Stress, and Abnormal Calcium Handling Mediate Diabetic Arrhythmic Risk.

Liu, Hong; Zhao, Yang; Xie, An; Kim, Tae-Yun; Terentyeva, Radmila; Liu, Man; Shi, Guangbin; Feng, Feng; Choi, Bum-Rak; Terentyev, Dmitry; Hamilton, Shanna; Dudley, Samuel C

Liu, Hong; Zhao, Yang; Xie, An; Kim, Tae-Yun; Terentyeva, Radmila; Liu, Man; Shi, Guangbin; Feng, Feng; Choi, Bum-Rak; Terentyev, Dmitry; Hamilton, Shanna; Dudley, Samuel C.

Afiliação

Liu H; Division of Cardiology, Department of Medicine, Lillehei Heart Institute, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.
Zhao Y; Division of Cardiology, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, China.
Xie A; Division of Cardiology, Department of Medicine, Lillehei Heart Institute, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.
Kim TY; Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Terentyeva R; Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Liu M; Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.
Shi G; Division of Cardiology, Department of Medicine, Lillehei Heart Institute, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.
Feng F; Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Choi BR; Division of Cardiology, Department of Medicine, Lillehei Heart Institute, University of Minnesota Twin Cities, Minneapolis, Minnesota, USA.
Terentyev D; Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Hamilton S; Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Dudley SC; Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio, USA.

JACC Basic Transl Sci ; 6(1): 42-52, 2021 Jan.

Article em En | MEDLINE | ID: mdl-33532665

Palavras-chave

APD, action potential duration; DM, diabetes mellitus; EAD, early afterdepolarization; IL, interleukin; IL-1RA, interleukin-1 receptor antagonist; Ito, transient outward potassium current; RyR2, ryanodine receptor; SR, sarcoplasmic reticulum; T1DM, type 1 diabetes mellitus; T2DM, type 2 diabetes mellitus; VT, ventricular tachycardia; calcium handling; inflammation; mitoROS, mitochondrial reactive oxygen species; mitochondria; oxidation; sudden cardiac death

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Risk_factors_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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