Back where it belongs: 11ß-hydroxyandrostenedione compels the re-assessment of C11-oxy androgens in steroidogenesis.

Barnard, Lise; du Toit, Therina; Swart, Amanda C

Barnard, Lise; du Toit, Therina; Swart, Amanda C.

Afiliação

Barnard L; Department of Biochemistry, Stellenbosch University, Private Bag X1, Matieland, 7602, South Africa.
du Toit T; Department of Biochemistry, Stellenbosch University, Private Bag X1, Matieland, 7602, South Africa.
Swart AC; Department of Biochemistry, Stellenbosch University, Private Bag X1, Matieland, 7602, South Africa; Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland, 7602, South Africa. Electronic address: acswart@sun.ac.za.

Mol Cell Endocrinol ; 525: 111189, 2021 04 05.

Article em En | MEDLINE | ID: mdl-33539964

Assuntos

Androgênios/metabolismo; Androstenodiona/análogos & derivados; Esteroides/biossíntese; Androstenodiona/química; Androstenodiona/metabolismo; Animais; Doença; Humanos; Esteroides/química

Palavras-chave

11-Ketotestosterone; 11ß-hydroxysteroid dehydrogenase (11ß-HSD); 21-Deoxycortisone (21 dF); 21-Hydroxylase deficiency (21OHD); Backdoor pathway; Castration resistant prostate cancer (CRPC); Congenital adrenal hyperplasia (CAH); Cushing's syndrome; Cytochrome P450 enzymes (CYP); Hirsutism; Oxygenated; Polycystic ovarian syndrome (PCOS)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esteroides / Androgênios / Androstenodiona Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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