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Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile.
Mieczkowski, Adam; Speina, Elzbieta; Trzybinski, Damian; Winiewska-Szajewska, Maria; Winska, Patrycja; Borsuk, Ewelina M; Podsiadla-Bialoskórska, Malgorzata; Przygodzki, Tomasz; Drabikowski, Krzysztof; Stanczyk, Lidia; Zhukov, Igor; Watala, Cezary; Wozniak, Krzysztof.
Afiliação
  • Mieczkowski A; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Speina E; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Trzybinski D; Biological and Chemical Research Centre, University of Warsaw, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Winiewska-Szajewska M; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Winska P; Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland.
  • Borsuk EM; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Podsiadla-Bialoskórska M; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Przygodzki T; Department of Haemostatic Disorders, Chair of Biomedical Sciences, Faculty of Health Sciences, Medical University of Lodz, 6/8 Mazowiecka Street, 92-235 Lodz, Poland.
  • Drabikowski K; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Stanczyk L; Department of Haemostatic Disorders, Chair of Biomedical Sciences, Faculty of Health Sciences, Medical University of Lodz, 6/8 Mazowiecka Street, 92-235 Lodz, Poland.
  • Zhukov I; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02-106 Warsaw, Poland.
  • Watala C; Department of Haemostatic Disorders, Chair of Biomedical Sciences, Faculty of Health Sciences, Medical University of Lodz, 6/8 Mazowiecka Street, 92-235 Lodz, Poland.
  • Wozniak K; Biological and Chemical Research Centre, University of Warsaw, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
Molecules ; 26(4)2021 Feb 03.
Article em En | MEDLINE | ID: mdl-33546456
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Caenorhabditis elegans / Nucleotídeo Cíclico Fosfodiesterase do Tipo 5 / Inibidores da Fosfodiesterase 5 / Tadalafila Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Caenorhabditis elegans / Nucleotídeo Cíclico Fosfodiesterase do Tipo 5 / Inibidores da Fosfodiesterase 5 / Tadalafila Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article