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7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo.
Kaniakova, Martina; Korabecny, Jan; Holubova, Kristina; Kleteckova, Lenka; Chvojkova, Marketa; Hakenova, Kristina; Prchal, Lukas; Novak, Martin; Dolezal, Rafael; Hepnarova, Vendula; Svobodova, Barbora; Kucera, Tomas; Lichnerova, Katarina; Krausova, Barbora; Horak, Martin; Vales, Karel; Soukup, Ondrej.
Afiliação
  • Kaniakova M; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic; Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic.
  • Korabecny J; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic.
  • Holubova K; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic; National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic.
  • Kleteckova L; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic; National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic.
  • Chvojkova M; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic; National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic.
  • Hakenova K; National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic.
  • Prchal L; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Novak M; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic; Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy, Charles University, Akademika Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic.
  • Dolezal R; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Hepnarova V; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic.
  • Svobodova B; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic.
  • Kucera T; Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic.
  • Lichnerova K; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic; Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic.
  • Krausova B; Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic.
  • Horak M; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic; Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic. Electronic address: martin.horak@iem.cas.cz.
  • Vales K; Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic; National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic. Electronic address: karel.vales@nudz.cz.
  • Soukup O; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic. Electronic address: ondrej.soukup@fnhk.cz.
Biochem Pharmacol ; 186: 114460, 2021 04.
Article em En | MEDLINE | ID: mdl-33571502
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tacrina / Receptores de N-Metil-D-Aspartato / Fármacos Neuroprotetores Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tacrina / Receptores de N-Metil-D-Aspartato / Fármacos Neuroprotetores Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article