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Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice.
Westermann, Lena Marie; Baranowsky, Anke; Di Lorenzo, Giorgia; Danyukova, Tatyana; Soul, Jamie; Schwartz, Jean-Marc; Hendrickx, Gretl; Amling, Michael; Rose-John, Stefan; Garbers, Christoph; Schinke, Thorsten; Pohl, Sandra.
Afiliação
  • Westermann LM; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
  • Baranowsky A; Clinic of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
  • Di Lorenzo G; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
  • Danyukova T; Telethon Institute of Genetics and Medicine (TIGEM), 80078, Pozzuoli, Italy.
  • Soul J; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
  • Schwartz JM; Skeletal Research Group, Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK.
  • Hendrickx G; School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PL, UK.
  • Amling M; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
  • Rose-John S; Center of Medical Genetics, Antwerp University Hospital and University of Antwerp, 2610, Edegem, Belgium.
  • Garbers C; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
  • Schinke T; Institute of Biochemistry, Christian-Albrechts-University of Kiel, 24098, Kiel, Germany.
  • Pohl S; Department of Pathology, Otto-Von-Guericke-University Magdeburg, 39120, Magdeburg, Germany.
Sci Rep ; 11(1): 3556, 2021 02 11.
Article em En | MEDLINE | ID: mdl-33574442
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Esqueleto / Interleucina-6 / Mucolipidoses Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Esqueleto / Interleucina-6 / Mucolipidoses Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article