Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.

Robichaud, Sabrina; Fairman, Garrett; Vijithakumar, Viyashini; Mak, Esther; Cook, David P; Pelletier, Alexander R; Huard, Sylvain; Vanderhyden, Barbara C; Figeys, Daniel; Lavallée-Adam, Mathieu; Baetz, Kristin; Ouimet, Mireille

Robichaud, Sabrina; Fairman, Garrett; Vijithakumar, Viyashini; Mak, Esther; Cook, David P; Pelletier, Alexander R; Huard, Sylvain; Vanderhyden, Barbara C; Figeys, Daniel; Lavallée-Adam, Mathieu; Baetz, Kristin; Ouimet, Mireille.

Afiliação

Robichaud S; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.
Fairman G; University of Ottawa Heart Institute, Ottawa, ON, Canada.
Vijithakumar V; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.
Mak E; University of Ottawa Heart Institute, Ottawa, ON, Canada.
Cook DP; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.
Pelletier AR; University of Ottawa Heart Institute, Ottawa, ON, Canada.
Huard S; University of Ottawa Heart Institute, Ottawa, ON, Canada.
Vanderhyden BC; Cancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Figeys D; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
Lavallée-Adam M; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.
Baetz K; Ottawa Institute of Systems Biology, Ottawa, ON, Canada.
Ouimet M; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.

Autophagy ; 17(11): 3671-3689, 2021 11.

Article em En | MEDLINE | ID: mdl-33590792

Assuntos

Autofagia; Colesterol/metabolismo; Células Espumosas/metabolismo; Gotículas Lipídicas/metabolismo; Técnicas de Silenciamento de Genes; Humanos; Gotículas Lipídicas/fisiologia; Proteoma/metabolismo; Saccharomyces cerevisiae/metabolismo; Ubiquitinação

Palavras-chave

Autophagy; cholesterol efflux; lipid droplet; lipolysis; lipophagy; macrophage foam cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Colesterol / Gotículas Lipídicas / Células Espumosas Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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